Hepu mitten crab (Eriocheir hepuensis)is mainly distributed along the coast of Guangxi. It has important economic value and breeding potential. There is no report on the edible yield and nutritional composition of HP. Therefore, this study used wild Chinese mitten crab (Eriocheir sinensis) in the Yangtze River as a control to determine and compare the edible yield, color parameters, total carotenoid content, proximate composition and fatty acid composition of wild HP and CJ adult crabs. The results showed: The edible yield of HP male was significantly lower than that of CJ male, but there was no significant difference in the gonadal index, hepatosomatic index and the meat yield between Hepu mitten crab and Chinese mitten crab; Regardless of male and female, the a^* and b^* values of the wet carapace of HP crab were significantly higher than those of CJ, and the total carotenoid content of HP male hepatopancreas was significantly higher than that of CJ male; The moisture of HP female in gonad was significantly higher than that of CJ female, but the lipid of muscle of HP female was significantly lower than that of CJ female,and the moisture and the protein content of HP male in muscle were significantly lower than those of CJ male;ΣSFA in HP female hepatopancreas, C18∶ln,ΣMUFA, DHA/ EPA in muscle and C18∶0, C20∶1n9 in ovaries were all significantly higher than CJ female,and HP male hepatopancreas contained higher C22∶6n3 and ΣPUFA while hepatopancreas had higher C22∶6n3, ΣPUFA than CJ male. In summary, similar tissue indices are found between HP and CJ, but there are differences in proximate composition, carotenoid content, and fatty acid composition. This may be related to their genetics and growth environment.