The molting and growth characters of Chinese mitten crab (Eriocheir sinensis) reared in the "Crab Palace" system for one molting cycle were studied. The results showed that the average increment rate of body weight of the crab was 33.19%, the average increment rate of carapace length, width and height ranged from 12.12% to 14.97%, and the average molting interval was 59.35 d. The average condition factor before molting was 60.84%, and the mean RGB value of body color in back carapace was 109.17, and the content of ecdysone hormone (EH) reached 14.18 IU/mL. In the "Crab Palace" system, no significant correlation (P>0.05) was observed between the growth status, EH content, molting interval before molting and increment rate of the growth traits after molting (P>0.05). The Chinese mitten crab reared in the "Crab Palace" system would start molting when its condition factor reached 60%, and ecdysone hormone content was more than 14 IU/mL.