How to control the potential ecological risks posed by heavy metals (HM) through the landscape regulation in coastal and estuary areas is a hot issue in wetland science. Taking the Yancheng coastal zone as a case, the landscape pattern changing process in 1975，1991，2000 and 2006, and their associated effects on HM accumulating were analyzed, integrating the spatial interpolation analysis of 6 HM of Cr，Cu，Fe，Mn，Ni and Zn. The result showed that the landscape changed dramatically from natural wetlands and barren lands in 1975 to fish ponds and farm lands in 2006. Artificial landscapes kept expanding while natural landscapes continued reducing. The landscape changing process reflected the development modes of the coastal areas. The HM analysis showed that the concentration of Cr，Cu，Mn，Ni，Zn had varied from the background values of 46.71, 20.22, 375.19, 21.68, and 60.69, to the values of 54.52, 19.14,548.83, 26.49, and 62.59（mg/kg）in 2007. It revealed a high correlation by the coupling analysis of landscape changing patterns and HM spatial concentration. How to establish quantitative coupling models of landscape pattern and process of HM accumulation to help regulating the landscape to reduce the regional ecological risks posed by HM is still a hot and hard question to be further studied.