In recent years, the people's life happiness index has become the key word in the government work report. Paying attention to the "life happiness index" is not only the embodiment of the "people-oriented" scientific development concept, but also the internal requirement of the harmonious development of economy and society.By means of questionnaire interview, 150 affected fishermen from Jingjiang District of Taizhou, Jiangsu Province, Jiangyin County of Wuxi, Wujin District of Changzhou, Yixing District of Wuxi, Wuzhong District of Suzhou and Wujiang District of Suzhou were selected as the research objects to analyze the current situation of life happiness of local affected fishermen and its influencing factors. The Generalized additive model （GAM） and life happiness index scale were built to analyze the factors affecting the happiness of life of affected fishermen.The study found that healthy physical condition, stable living pattern, increasing household expenditure, good living environment and higher education level were the main factors that made fishermen satisfied with their lives. Unhealthy physical condition, unstable life pattern, lack of long-term money planning awareness and reasonable control of consumption expenditure after having a certain amount of savings, and the number of two or more children living independently are the main factors that lead to fishermen's dissatisfaction with life. The government can improve the life happiness index of affected fishermen by relaxing housing conditions, creating new jobs, carrying out spiritual civilization construction, training on the prevention of common diseases, building new public activity facilities and other measures.