The impact of ocean acidification on the changes of marine species abundance is a hot topic. East Bering Sea is rich in fishery resources and the sea area is at greater potential risk from ocean acidification. This study explored the 70 species' abundance variations (including fishes, crustaceans and mollusks) and its relationship with bottom seawater pH in this area by dynamic regression model. Results showed that 27.78%, 36.84% and 33.33% of the species abundance of fish, mollusks and crustaceans were affected by the changes of pH respectively. The responses of species abundance to pH decrease were different, including three kinds, i.e. up, down, and up first, then down. These responses could be result from the change of habitat environment or suitable habitat range under pH variations. Our results indicated that it is not enough to analyze the species abundance only by pH. Ocean acidification would have different types of impact on the abundance of fishery species. This study could provide a reference for the sustainable development and utilization of fishery species under future ocean acidification.