Taking a typical square chamfered aquaculture pond as the research object, a numerical model of the liquid-solid two-phase flow field was established,and the influence of the slope of the pond bottom surface and hydrodynamic conditions on its water purification efficiency was analyzed. Studies have shown that as the internal pressure of the aquaculture pond decreases, the forces on the particulate matter decrease and the sediment concentration increases; When the rotation speed of the flow is constant, the separation efficiency of the particles increases with the increase of the bottom slope; when the rotation speed of the flow is 0.25 rad/s and the bottom slope is 12 °, the water purification efficiency of the aquaculture pond is the highest; The numerical calculation results are in good agreement with the experimental data, verifying the effectiveness of the numerical calculation method. The research results have important scientific significance and engineering application value for the optimal design of the pond water circulation aquaculture system, the evaluation of the hydrodynamic conditions of fish survival, the solution to the problems of low water circulation efficiency and low efficiency of sewage collection.