To investigate the relationship between growth properties and thermal and high salt tolerance in Sinonovacula constricta, We have established and obtained 27 families with different growth performance of Sinonovacula constricta in 2014 based on the excellent group from Leqing Bay. Growth traits of different families were recorded in the first three months:Five families showed superior growth rate, seventeen families showed medium growth rate and five families showed inferior growth. After the next three months, five superior and inferior families were obtained respectively. In the preliminary experiment, the semi-lethal temperature and salinity of Sinonovacula constricta are 36.5℃ and 35.8 respectively. With the control group of group breeding Sinonovacula constricta, each families were cultivated in the environment of normal salinity, 36.5℃ water or normal temperature, 35.8 salinity respectively. To conclude, the survival rate of superior families was higher than the disadvantage families under the conditions of semi-lethal temperature and salinity and there was a significant difference in heat tolerance and salt tolerance among the different families studied(P<0.05) by multiple comparison and variance analysis. The strongest family were higher than the worst family by 74% and 50% respectively in upper thermal and salt tolerance.