We have cultivated the female broodstock of half smooth tongue sole intensively by using nereid from 11th April 2012 to 3rd October 2012. It turned out that the females grew rapidly and the gonad development had been brought forward, the duration of spawning had been extended, egg laying amount, fertilization rate, hatching rate, etc. had risen notably,and mortality rate had a significant reduction which was the most important. After 4 months culturing, the average body weight of Group A rose from 1.25 kg to 1.85 kg, the net gain and average daily gain were 0.6 kg and 4.92 g/d respectively, which were significantly higher than those of Group B,which were 0.34 kg and 2.79 g/d respectively. Before spawning, 118 individuals had matured, the mature rate was 59.60%. However, only in 67 individuals in Group B the gonad had matured, the mature rate was 33.84%. In Group A, 11 individuals were dead, the mortality rate was 9.32%, by contrast, there were 28 individuals dead and the mortality rate was 41.79%, which was much higher than 32.47% over Group A. Gonad of parental fish of Group A began to develop on 26th May, which was 19 days earlier than Group B, and it began to spawn on 10th September, which was 6 days earlier. The spawning duration of Group A was 24 days, 13 days were extended compared with Group B. Mean fecundity and mean floating eggs were 411.3 mL and 263.2 mL separately, which was 60.6 mL and 71.2 mL higher than Group B respectively, also the average of floating rate of Group A (80.97%) was notably higher than Group B (67.65%). The fertilization rates of the 2 groups were 60.37% and 47.29% separately. Group A was 13.08% higher than Group B. The hatching rates of the 2 groups were 53.28% and 22.40%, Group A was 2.38 times as much as Group B. Both of the 2 groups’ aberration rates were low, 2.36% and 4.73% separately, however, Group A was less than half of Group B.