Dosidicus gigas is a short lived species and its recruitments would be affected by change of environmental conditions. Based on the fishing data collected by Chinese squid jigger fleets, and sea surface temperature (SST) and Nino 1+2 SSTA data, in the high sea waters of Southeastern Pacific Ocean from 2003 to 2010, the grey correlations between the proportion of favorable SST in the fishing ground and spawning ground (indicated by PF and _S, respectively) are analyzed, and the relationship between PF,_S and CPUE are also analyzed to evaluate the effect of changable environment on recruitment of D. gigas respectively. The results indicated that the largest proportions of favorable SST in fishing ground are from September to November, and from December to January of the next year for the spawning ground. The grey correlation between the Ps and Nino 1+2 SSTA is higher than that between the PF and Nino 1+2 SSTA, which shows that the effect of Nino 1+2 SSTA on spawning ground is significant. Meanwhile, the correlation between Ps and CPUE is higher with the value of above 0.4 and exhibits continuity in time from November to February of the next year. The results indicated that the La Nina condition could increase the proportion of favorable SST in the fishing ground and form the wide upwelling, which is beneficial to D. gigas’ feeding and growth, and improve the recruitment of D. gigas. Otherwise, the adverse environmental condition will be not helpful to the recruitment of D. gigas.