This trial investigated the effects of garlic stem powder and oregano leaf powder on growth performance, digestive enzyme activity and serum biochemical indexes of the mirror carp (Cyprinus carpio L.minor) .A total of seven trial treatment groups: G1 was control group, G2 added 10 mg/kg Flavomycin, G3, G4 added 0.5% and 2.5% garlic stem powder respectively, G5, G6 added 0.1% and 0.5% oregano leaf powder respectively, G7 added 0.5% garlic stem powder and 0.5% powder.Each treatment had 3 replicates of 10 fish with initial body weight (201.45±16.25) g.The feeding trial was conducted for 8 weeks.The results showed: Compared with G1 and G2, the specific growth rate and weight gain rate were increased and feed conversion rate was reduced significantly of G3 garlic group (P<0.05) ;the efficiency of the protein was increased significantly of G3, G4 garlic group and G5, G6 oregano group (P<0.05) .Compared with G1, the activity with protease and lipase in hepatopancreas and protease in foregut and midgut were significantly increased of G3 garlic group (P<0.05) ;the protease activity in hepatopancreas was significantly increased of G4 garlic group (P<0.05) ;the amylase and lipase activity in intestinal were significantly higher of G5, G6, G7 than of G1, G2 (P<0.05) .Compared with G1, the TP, ALB and GLB were increased significantly of G3, G6 and G7 (P<0.05) ;CHOL, ALT and AST of G2 were significantly reduced (P<0.05) .Conclusion: the feed with 0.5% garlic stem powder can effectively improve the growth performance;but oregano leaf powder can't promote the growth of the mirror carp significantly.