This paper deals with key techniques of large scale artificial propagation and breeding of S.meridionalis larvae.The results indicated that it was quite effective to induce spawning for female S.meridionalis by mesns of two kinds of mixed oxytocic hormones.The two kinds of mixed oxytocic hormones were (HCG+PG+LRH-A 2) and (oxytocic efficaciousness +LRH-A 2) .HCG is human chorionic gonadotrophin,PG is pituitary gland of Cyprinus carpio L.,and LRH-A 2 is luleinizing hormone releasing homone analogue.Their rates to induce spawning were 100%.The fertilization rate of eggs had close relationship with artificial fertilizing methods.The survial rates of larvae breeding were affected remarkably by opening mouth times of fries and sufficient or insufficient diets.The experiment showed that the fittest period of opening mouth of fries was from an hour before yolk sac disappearing to an hour after yolk sac disappearing completely.The main reason of survial rate decreasing on larvae breeding was caused by insufficient diet.The individuals of breeding larvae over 3 centimeter was 7.422 million individuals and the average survial rate was 80.67% when 9.2 million inidviduals of S.meridionalis fries were bred.