This paper reports the variations in growth performance of Chinese mitten crab (Eriocheir sinensis) originated from the Yangtze and Liaohe River, cultured in the pens seated at the Rushan Lake, Huhe river system, Anhui Province. (1)The growth rate of two crabs from two river systems appeared a slight difference in various months, compared with the Liaohe river crab, the Yangtze river crab showed a lower growth rate from March to July without significant difference (P>0.05), but better from August to October significantly (P<0.01). (2)Compared with the Yangtze river crab, the breeding molting and spawning migration of the Liaohe river crab was 30 days earlier respectively. (3)The harvest size, body weight gain and recapture rate of stocking seed between these two crabs were different significantly (P<0.01). Comprehensively say, the growth performance of the crab from the Yangtze river was better than the crab from the Liaohe river when they cultured in pens at lakes of the Huaihe River system.